Feasibility of a randomised clinical trial for physiotherapy intervention in patients at high risk of early-onset knee osteoarthritis and symptomatic decline following anterior cruciate ligament reconstruction

Following anterior cruciate ligament (ACL) rupture and surgical reconstruction (ACLR), individuals typically undergo a prolonged period of rehabilitation (6-12 months) to optimise muscle strength, neuromuscular control, and confidence to ultimately facilitate a return to physical activity and competitive sport. Despite successful recovery and return to activities, approximately 50% of individuals develop early knee osteoarthritis within 10 years of injury.

There is limited evidence regarding the most appropriate rehabilitation program to optimise patient outcomes following ACLR, particular for individuals at highest risk of developing early knee osteoarthritis. The type of exercise, the technique, intensity and frequency at which it is performed, duration and level of supervision of a rehabilitation program are all factors that must be considered in designing and implementing programs.

This Australian Physiotherapy Association funded research project investigates the feasibility of a randomised clinical trial for physiotherapy intervention in patients at high risk of early-onset knee osteoarthritis and symptomatic decline following ACLR.

Staff involved: Brooke Patterson, Adam Culvenor, Kay Crossley, Christian Barton, Randall Cooper

Study Protocol: 

https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=373730